From Colony to Community: Ste-Sophie, Quebec

Medical management: From colony to community

In this article the development from the colonies founded in the 19th century to the current situation is discussed. Future development is not to simply follow the slogan 'to the community' translated as 'epilepsy must be treated in general hospitals' but to preserve epileptology as specialized care with 'centres of excellence' orchestrated by coupling epilepsy centres with academical neurology.

Sophie Racine

The first [4+2]-annulation between aminocyclobutanes and aldehydes to access tetrahydropyranyl amines is reported. With phthalimido cyclobutane dicarboxylates and aromatic aldehydes, tetrahydropyrans were obtained in 53-92% yield and 3:117:1 dr using scandium triflate or iron trichloride as catalyst. The use of thymineor fluorouracilsubstituted cyclobutanes gave direct access to six-membered ri...

An Oval Tube Adapter for the Quebec Colony Counter.

Ste 11 Ste 7 Fus 3 Ste 5 scaffold Ste 12 FUS 1 promoter His 3 transcription Activated receptor Ligand Receptor

Background: Heterotrimeric G proteins are important for numerous signaling events in eukaryotes, serving primarily to transduce signals that are initiated by G protein-coupled receptors. It has recently become clear that nonreceptor activators can regulate the level of heterotrimeric G protein signaling and, in some cases, drive cycles of receptor-independent G protein activation. In this study...

Large Sophie Germain primes

If P is a prime and 2P+1 is also prime, then P is a Sophie Germain prime. In this article several new Sophie Germain primes are reported, which are the largest known at this time. The search method and the expected search times are discussed.